EPIDEMIOLOGY AND CLINICAL CHARACTERISTICS OF PERIPHERAL NERVE TUMORS: A 13-YEAR RETROSPECTIVE ANALYSIS

  • Andra Elena Martin “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
  • Cristina Gorgan Clinic of Neurosurgery, Emergency Clinical Hospital “Bagdasar Arseni”, Bucharest, Romania
  • Mircea Radu Gorgan “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania & Clinic of Neurosurgery, Emergency Clinical Hospital “Bagdasar Arseni”, Bucharest, Romania
Keywords: peripheral nerve tumors, schwannomas, epidemiology

Abstract

Peripheral nerve tumors, though relatively rare, represent a significant subset of soft tissue neoplasms. This study aims to provide a comprehensive retrospective analysis of clinical and epidemiological characteristics of peripheral nerve tumors treated at Bagdasar Arseni Hospital in Bucharest from 2010 to 2023. This observational study analyzed 285 cases of peripheral nerve tumors, evaluating tumor localization, histological types, gender and age distribution, and presenting symptoms. Data were statistically analyzed to identify patterns and correlations. Of the 285 patients, 153 were female and 132 were male. Schwannomas were the most common tumor type, accounting for 82.81% (236 cases), followed by neurofibromas (12.28%, 35 cases) and neurinomas (4.91%, 14 cases). The mean age of patients was 52.0 years. Pain was reported in 25.61% of cases, while headache and vertigo were noted in 41.40% and 35.79% of cases, respectively. Motor and sensory disturbances were more common in limb tumors. The study highlights the predominance of schwannomas and their association with middle-aged adults. Gender distribution showed a slight female predominance. Significant age and symptom variations were observed across tumor types and locations. These findings underscore the importance of personalized diagnostic and therapeutic approaches, considering tumor type, patient age, and anatomical location. Routine imaging and early detection remain crucial for improving clinical outcomes in peripheral nerve tumor management.

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Published
2023-12-27
How to Cite
[1]
A. Martin, C. Gorgan, and M. Gorgan, “EPIDEMIOLOGY AND CLINICAL CHARACTERISTICS OF PERIPHERAL NERVE TUMORS: A 13-YEAR RETROSPECTIVE ANALYSIS”, JSS, vol. 10, no. 4, Dec. 2023.