A CASE OF OVARIAN CARCINOID TUMOUR

CLINICAL CASE

Abstract

Primary ovarian carcinoid tumours are rare neoplasms. Carcinoid tumours mostly occur in the gastrointestinal tract and the lungs. Ovarian carcinoid tumours constitute only 0.5% of all carcinoid tumours and <0.1% of all ovarian carcinomas. Conventional tumour pathology criteria and DNA cytometry have limited value in assessing the malignancy of a neuroendocrine tumour. Hence, the detection of substances that are more specific for carcinoid tumours can facilitate a more exact diagnosis. Two markers are primarily used to diagnose and follow carcinoid tumours: 5-hydroxyindoleacetic acid (5-HIAA) and chromogranin A (CgA).We present the case of a 35-year-old female without personal pathological antecedents, diagnosed with right ovarian tumour at an ultrasound examination, without any clinical symptoms, for which she underwent right ovarectomy in January 2015, with histopathological diagnosis of stromal carcinoid (well differentiated neuroendocrine tumour) and immunohistological result of well differentiated G1 ovarian tumour. At present, the patient is under periodical endocrinological monitorization. 5-hydroxyindoleacetic acid, serotonin and chromogranin A levels are in normal ranges currently. Preoperatively there was no endocrinological evaluation or specific blood test examination with biochemical markers.