RISK FACTORS IMPACT THE INCIDENCE OF SURGICAL COMPLICATION RECURRENCE IN CROHN'S DISEASE
Keywords:
Crohn disease, risk factors, treatment
Abstract
Various risk factors are associated with early surgery in a patient diagnosed with Crohn's Disease, such as tobacco use, disease localization, fibrostenotic phenotype, and early use of immunomodulatory therapy or high-dose glucocorticoids. Age, sex, location of the disease, duration, and presence of granulomas all have a different impact on postoperative recurrence. Apart from smoking other factors have not been established that could affect recurrence. Our study aims based on a specific group of patients to evaluate the impact on the frequency of surgical relapse of age, smoking status, and living environment (urban or rural).
References
[1] A Aujnarain, DR Mack, EI Benchimol. The role of the environment in the development of pediatric inflammatory bowel disease. Curr Gastroenterol Rep 2013; 15:326.
[2] IS Soon, NA Molodecky, DM Rabi, et al. The relationship between urban environment and the inflammatory bowel diseases: a systematic review and meta-analysis. BMC Gastroenterol 2012; 12:51.
[3] N To, DJ Gracie, AC Ford. Systematic review with meta-analysis: the adverse effects of tobacco smoking on the natural history of Crohn's disease. Aliment Pharmacol Ther. 2016, 43(5):549-61.
[4] S Scharrer, D Lissner, C Primas, W Reinisch, G Novacek, S Reinisch, P Papay, C Dejaco, H Vogelsang, W Miehsler. Passive Smoking Increases the Risk for Intestinal Surgeries in Patients with Crohn's Disease. Inflamm Bowel Dis. 2021; 27(3):379-385.
[5] VO Shaffer, SD Wexner. Surgical management of Crohn’s disease. Langenbecks Arch Surg 2013; 398: 13–27.
[6] I Slavu, L Alecu, A Tulin, D Mihăilă, V Braga, T Voiosu, L Tomescu, S Constantinoiu. Reintervention Rate Following Emergency Surgery for Crohn Disease Chirurgia 2018; No.2:113
[7] M Zhao, L Gönczi, PL Lakatos, J Burisch. The Burden of Inflammatory Bowel Disease in Europe in 2020. J Crohns Colitis. 2021; 15(9):1573-1587.
[8] IC Solberg, MH Vatn, O Hoie, et al. Clinical course in Crohn s disease: results of a Norwegian population-based ten-year follow up study. Clin Gastroenterol Hepatol. 2007; 5:1430–1438.
[9] WPW Chan, F Mourad, RW Leong. Crohn's disease associated strictures. J Gastroenterol Hepatol. 2018; 33(5):998-1008.
[10] W Bednarz, P Czopnik, B Wojtczak, R Olewiński, P Domosławski, J Spodzieja. Analysis of results of surgical treatment in Crohn’ s disease. Hepatogastroenterology 2008; 55: 998-1001
[11] C Stöss, M Berlet, S Reischl, U Nitsche, MC Weber, H Friess, D Wilhelm, PA Neumann. Crohn's disease: a population-based study of surgery in the age of biological therapy. Int J Colorectal Dis. 2021; 36(11):2419-2426.
[12] L Petagna, A Antonelli, C Ganini, V Bellato, M Campanelli, A Divizia, C Efrati, M Franceschilli, AM Guida, S Ingallinella, F Montagnese, B Sensi, L Siragusa, GS Sica. Pathophysiology of Crohn's disease inflammation and recurrence. Biol Direct. 2020; 15(1):23.
[13] C Bähler, AM Schoepfer, SR Vavricka, B Brüngger, O Reich. Chronic comorbidities associated with inflammatory bowel disease: prevalence and impact on healthcare costs in Switzerland. Eur J Gastroenterol Hepatol. 2017 29(8):916-925.
[14] B Veauthier, JR Hornecker. Crohn's Disease: Diagnosis and Management. Am Fam Physician. 2018, 98(11):661-669.
[15] RA John, RB Gearry. Smoking Cessation for Patients with Crohn Disease: Not Just for the Patient? Inflamm Bowel Dis. 2021, 27(3):386-387.
[16] JJ Rozich, A Holmer, S Singh. Effect of Lifestyle Factors on Outcomes in Patients with Inflammatory Bowel Diseases. Am J Gastroenterol. 2020, (6):832-840.
[17] N Heerasing, NA Kennedy. Interaction Between NOD2 and Smoking in the Pathogenesis of Crohn's Disease. EBioMedicine. 2017; 21:49-50.
[18] S Inamdar, A Volfson, L Rosen, S Sunday, S Katz, K Sultan. Smoking and early infliximab response in Crohn’s disease: a meta-analysis. J Crohns Colitis. 2015; 9(2):140-6.
[19] GG Kaplan. Smoking Cessation for Crohn's Disease: Clearing the Haze. Am J Gastroenterol. 2016; 111(3):420-2.
[20] J Karczewski, B Poniedziałek, P Rzymski, A Rychlewska-Hańczewska, Z Adamski, K Wiktorowicz. The effect of cigarette smoking on the clinical course of inflammatory bowel disease. Prz Gastroenterol. 2014;9(3):153-9.
[21] CN Bernstein, JF Blanchard, P Rawsthorne, A Wajda: Epidemiology of Crohn's disease and ulcerative colitis in a central Canadian province: a population-based study. Am J Epidemiol. 1999, 149: 916-924.
[22] IS Soon, NA Molodecky, DM Rabi, WA Ghali, HW Barkema, GG Kaplan. BMC Gastroenterol. 2012; 12: 51.
[23] A Sonnenberg. Demographic characteristics of hospitalized IBD patients. Dig Dis Sci 2009; 54: 2449 – 55.
[24] YS Jung, DI Park, BD Ye, JH Cheon, YS Kim, YH Kim, JS Kim, HS Chae, GH Baik, DS Han. Long-term Clinical Outcomes of Urban Versus Rural Environment in Korean Patients with Crohn’s Disease: Results from the CONNECT Study Journal of Crohn's and Colitis, 2015; 9:246–251
[25] EI Benchimol, D Gilaad, G Kaplan. MPH Rural and Urban Residence During Early Life is Associated with Risk of Inflammatory Bowel Disease: A Population-Based Inception and Birth Cohort Study. The American Journal of Gastroenterology 2007, 112:1412–1422.
[26] SL Popa, C Pop, DL Dumitrascu. Diet Advice for Crohn's Disease: FODMAP and Beyond. Nutrients. 2020; 12(12):3751.
[27] M Gajendran, P Loganathan, AP Catinella, JG Hashash. A comprehensive review and update on Crohn's disease. Dis Mon. 2018 ;64(2):20-57.
[28] IC Solberg, MH Vatn, O Hoie, et al. Clinical course in Crohn s disease: results of a Norwegian population-based ten-year follow up study. Clin Gastroenterol Hepatol. 2007; 5:1430–1438.
[29] R Horne, R Parham, R Driscoll, A Robinson Patients' attitudes to medicines and adherence to maintenance treatment in inflammatory bowel disease. Inflamm Bowel Dis. 2009; 15(6):837.
[2] IS Soon, NA Molodecky, DM Rabi, et al. The relationship between urban environment and the inflammatory bowel diseases: a systematic review and meta-analysis. BMC Gastroenterol 2012; 12:51.
[3] N To, DJ Gracie, AC Ford. Systematic review with meta-analysis: the adverse effects of tobacco smoking on the natural history of Crohn's disease. Aliment Pharmacol Ther. 2016, 43(5):549-61.
[4] S Scharrer, D Lissner, C Primas, W Reinisch, G Novacek, S Reinisch, P Papay, C Dejaco, H Vogelsang, W Miehsler. Passive Smoking Increases the Risk for Intestinal Surgeries in Patients with Crohn's Disease. Inflamm Bowel Dis. 2021; 27(3):379-385.
[5] VO Shaffer, SD Wexner. Surgical management of Crohn’s disease. Langenbecks Arch Surg 2013; 398: 13–27.
[6] I Slavu, L Alecu, A Tulin, D Mihăilă, V Braga, T Voiosu, L Tomescu, S Constantinoiu. Reintervention Rate Following Emergency Surgery for Crohn Disease Chirurgia 2018; No.2:113
[7] M Zhao, L Gönczi, PL Lakatos, J Burisch. The Burden of Inflammatory Bowel Disease in Europe in 2020. J Crohns Colitis. 2021; 15(9):1573-1587.
[8] IC Solberg, MH Vatn, O Hoie, et al. Clinical course in Crohn s disease: results of a Norwegian population-based ten-year follow up study. Clin Gastroenterol Hepatol. 2007; 5:1430–1438.
[9] WPW Chan, F Mourad, RW Leong. Crohn's disease associated strictures. J Gastroenterol Hepatol. 2018; 33(5):998-1008.
[10] W Bednarz, P Czopnik, B Wojtczak, R Olewiński, P Domosławski, J Spodzieja. Analysis of results of surgical treatment in Crohn’ s disease. Hepatogastroenterology 2008; 55: 998-1001
[11] C Stöss, M Berlet, S Reischl, U Nitsche, MC Weber, H Friess, D Wilhelm, PA Neumann. Crohn's disease: a population-based study of surgery in the age of biological therapy. Int J Colorectal Dis. 2021; 36(11):2419-2426.
[12] L Petagna, A Antonelli, C Ganini, V Bellato, M Campanelli, A Divizia, C Efrati, M Franceschilli, AM Guida, S Ingallinella, F Montagnese, B Sensi, L Siragusa, GS Sica. Pathophysiology of Crohn's disease inflammation and recurrence. Biol Direct. 2020; 15(1):23.
[13] C Bähler, AM Schoepfer, SR Vavricka, B Brüngger, O Reich. Chronic comorbidities associated with inflammatory bowel disease: prevalence and impact on healthcare costs in Switzerland. Eur J Gastroenterol Hepatol. 2017 29(8):916-925.
[14] B Veauthier, JR Hornecker. Crohn's Disease: Diagnosis and Management. Am Fam Physician. 2018, 98(11):661-669.
[15] RA John, RB Gearry. Smoking Cessation for Patients with Crohn Disease: Not Just for the Patient? Inflamm Bowel Dis. 2021, 27(3):386-387.
[16] JJ Rozich, A Holmer, S Singh. Effect of Lifestyle Factors on Outcomes in Patients with Inflammatory Bowel Diseases. Am J Gastroenterol. 2020, (6):832-840.
[17] N Heerasing, NA Kennedy. Interaction Between NOD2 and Smoking in the Pathogenesis of Crohn's Disease. EBioMedicine. 2017; 21:49-50.
[18] S Inamdar, A Volfson, L Rosen, S Sunday, S Katz, K Sultan. Smoking and early infliximab response in Crohn’s disease: a meta-analysis. J Crohns Colitis. 2015; 9(2):140-6.
[19] GG Kaplan. Smoking Cessation for Crohn's Disease: Clearing the Haze. Am J Gastroenterol. 2016; 111(3):420-2.
[20] J Karczewski, B Poniedziałek, P Rzymski, A Rychlewska-Hańczewska, Z Adamski, K Wiktorowicz. The effect of cigarette smoking on the clinical course of inflammatory bowel disease. Prz Gastroenterol. 2014;9(3):153-9.
[21] CN Bernstein, JF Blanchard, P Rawsthorne, A Wajda: Epidemiology of Crohn's disease and ulcerative colitis in a central Canadian province: a population-based study. Am J Epidemiol. 1999, 149: 916-924.
[22] IS Soon, NA Molodecky, DM Rabi, WA Ghali, HW Barkema, GG Kaplan. BMC Gastroenterol. 2012; 12: 51.
[23] A Sonnenberg. Demographic characteristics of hospitalized IBD patients. Dig Dis Sci 2009; 54: 2449 – 55.
[24] YS Jung, DI Park, BD Ye, JH Cheon, YS Kim, YH Kim, JS Kim, HS Chae, GH Baik, DS Han. Long-term Clinical Outcomes of Urban Versus Rural Environment in Korean Patients with Crohn’s Disease: Results from the CONNECT Study Journal of Crohn's and Colitis, 2015; 9:246–251
[25] EI Benchimol, D Gilaad, G Kaplan. MPH Rural and Urban Residence During Early Life is Associated with Risk of Inflammatory Bowel Disease: A Population-Based Inception and Birth Cohort Study. The American Journal of Gastroenterology 2007, 112:1412–1422.
[26] SL Popa, C Pop, DL Dumitrascu. Diet Advice for Crohn's Disease: FODMAP and Beyond. Nutrients. 2020; 12(12):3751.
[27] M Gajendran, P Loganathan, AP Catinella, JG Hashash. A comprehensive review and update on Crohn's disease. Dis Mon. 2018 ;64(2):20-57.
[28] IC Solberg, MH Vatn, O Hoie, et al. Clinical course in Crohn s disease: results of a Norwegian population-based ten-year follow up study. Clin Gastroenterol Hepatol. 2007; 5:1430–1438.
[29] R Horne, R Parham, R Driscoll, A Robinson Patients' attitudes to medicines and adherence to maintenance treatment in inflammatory bowel disease. Inflamm Bowel Dis. 2009; 15(6):837.
Published
2022-12-25
How to Cite
[1]
I. Slavu, “RISK FACTORS IMPACT THE INCIDENCE OF SURGICAL COMPLICATION RECURRENCE IN CROHN’S DISEASE”, JSS, vol. 9, no. 4, Dec. 2022.
Section
Articles
