ACUTE FATTY LIVER OF PREGNANCY- CASE REPORT AND REVIEW OF LITERATURE
Acute fatty liver disease (AFLP) is a rare, potentially fatal complication that occurs in the third trimester of pregnancy or in the early postpartum period, being first described by Sheehan in 1940, representing an obstetrical emergency. Although the exact pathogenesis is unknown, this disease has been linked to an abnormality in fetal fatty acid metabolism, characterized by fatty microvesicular infiltration of hepatocytes without inflammation or necrosis. Although the Swansea Criteria have been developed to diagnose acute fatty liver pregnancy, there is a large clinical overlap between AFLP, HELLP syndrome and severe preeclampsia, and it is often impossible to make a clear diagnosis between them. We present the case of a 38-year-old patient, with 36-week pregnancy, biparous, after a caesarean section 7 years ago, who presented to the emergency unit, in the obstetrics-gynecology service of a multidisciplinary hospital, directed by the attending physician for severe jaundice, alcoholic stools, nausea, vomiting, epigastric pain.
Keywords: acute fatty liver disease, obstetrical emergency, fatty acid metabolism, HELLP syndrome, severe preeclampsia, jaundice
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