MEIGS SYNDROME IN OVARIAN FIBROTHECOMA WITH ELEVATED CA-125  – A CASE REPORT

Adina Elena Nenciu; Mihai Cristian Dumitrașcu; Cristian Peteu; Florica Șandru; Cătălin George Nenciu; Andreea Ilieșiu; George Simion; Ana Maria Oproiu

doi:10.33695/jss.v8i2.441

Adina Elena Nenciu 2Department of Obstetrics and Gynecology, University Emergency Hospital, Bucharest, Romania
Mihai Cristian Dumitrașcu “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania & Department of Obstetrics and Gynecology, University Emergency Hospital, Bucharest, Romania
Cristian Peteu Department of Obstetrics and Gynecology, University Emergency Hospital, Bucharest, Romania
Florica Șandru “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania & Department of Dermatology, Elias Emergency University Hospital, Bucharest, Romania
Cătălin George Nenciu “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania & Department of Obstetrics and Gynecology, “Sf. Ioan” Clinical Emergency Hospital - “Bucur” Maternity, Bucharest, Romania
Andreea Ilieșiu “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania & Department of Pathological Anatomy, Bucharest University Emergency Hospital, Bucharest, Romania
George Simion Department of Pathological Anatomy, Bucharest University Emergency Hospital, Bucharest, Romania
Ana Maria Oproiu “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania & Department of Plastic and Reconstructive Surgery, Bucharest University Emergency Hospital, Bucharest, Romania

DOI: https://doi.org/10.33695/jss.v8i2.441

Keywords: ovarian tumor, fibrothecoma ovary, Meigs syndrome, ascites, hydrothorax.

Abstract

Benign and malignant ovarian tumors are frequently encountered in patients of all ages. The cell line from which they develop is represented by germ cell, stromal cell, and epithelial cell. Ovarian fibrothecoma is a tumor that develops from the stromal sex cord and has characteristics specific to fibroma and thecoma. Fibrothecomas represent 1.2% of benign and malignant ovarian tumors and are associated with slow development and common symptoms. Meigs syndrome represents the presence of benign ovarian tumors with ascites and hydrothorax that are resolved after the surgical excision of the tumor. The tumors described in this case are fibroma, thecoma, Brenner tumor, or granulosa cell tumor.In this paper, we present the case of a 49-year-old patient that presented to our clinic for pelvi-abdominal mass. Computerized pelvic tomography showed an engorged uterus with transaxial dimensions of 123 mm by 83 mm, with intrauterine material of 58 mm, non-iodofilic. The ovary and annexes were normal. Lateral to the uterus, a well-defined, 230/180 mm diameter, tissue-shaped, nodular mass was identified, without precise origin. Also, the CT scan showed pleural effusion (37 mm) and ascites. After the patient was stabilized and the surgery was performed, the histopathological result shown fibrothecoma ovary.

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