RECURRENCE OF MALIGNANT PERIPHERAL NERVE SHEATH TUMOR

  • Alin Istodor First Department of Surgery, Second Discipline of Surgical Semiology, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania & Department of General Surgery and Surgical Oncology, Municipal Emergency Clinical Hospital, Timișoara, Romania
  • Ovidiu Ardelean First Department of Surgery, Second Discipline of Surgical Semiology, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania & Department of General Surgery and Surgical Oncology, Municipal Emergency Clinical Hospital, Timișoara, Romania
  • Carmen Rădulescu Department of General Surgery and Surgical Oncology, Municipal Emergency Clinical Hospital, Timișoara, Romania
  • Octavian Mazilu First Department of Surgery, Second Discipline of Surgical Semiology, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania & Department of General Surgery and Surgical Oncology, Municipal Emergency Clinical Hospital, Timișoara, Romania
Keywords: malignant peripheral nerve sheath tumor, recurrence, sarcoma

Abstract

Peripheral nerve sheath tumor (PNST) is known as a benign tumor called Schwannomas, developed from the Schwann cells that produce myelin and collagen, and can occur in a wide variety of locations. In some cases, it can take a malignant turn and grow as a pelvic mass known as malignant peripheral nerve sheath tumor (MPNST), malignant schwannoma, malignant neurofibroma, malignant mesenchynoma and neurogenic sarcoma. Our case report presents a female patient presenting dysuria and pelvic pain. The clinical examination revealed a palpable mass in the lower abdomen. The computer tomography (CT) scan of the abdomen and pelvic region showed a tumor mass that was in contact with the nearby organs, but not infiltrating them. After the surgery, histopathology confirmed the MPNST proliferation. A month after, the patient returned for a follow-up and presenting pelvic pain. The CT scan of the abdomen and pelvic region showed a tumoral mass compressing the nearby organs, but not infiltrating them. The patient was referred to oncology board for palliative treatment. The particularity of this case report is the short period of time recurrence of the MPNST, rather than metastases. The most important treatment for MPNSTs remains surgery, trying to achieve negative margins. However, there have been reported two cases of unresectable MPSNT with partial remission to chemo- and radiotherapy.

 

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Published
2021-02-24
How to Cite
[1]
A. Istodor, O. Ardelean, C. Rădulescu, and O. Mazilu, “RECURRENCE OF MALIGNANT PERIPHERAL NERVE SHEATH TUMOR”, JSS, vol. 7, no. 4, pp. 145-148, Feb. 2021.