THE IMPACT OF UTERINE FIBROMATOSIS ON THE ENDOMETRIUM AND FERTILITY
Uterine fibroids are the most common benign tumor that can be found in a woman's reproductive
system. The uterine fibroid affects millions of women globally each year and we can consider this
pathology, without exaggerating, an important public health problem. Our study was carried out
prospectively, in 5 years (2015-2019) and enrolled 480 patients selected with uterine fibroid, from a
number of 28809 women who were hospitalized during this period in the university clinic of
Obstetrics and Gynecology within the „Saint Pantelimon” Emergency Hospital, Bucharest, Romania.
Patients were divided into two groups of study: Group A, those with well-defined, single or multiple
uterine fibroid and Group B – patients with diffuse uterine fibromatosis. The clinical,
histopathological and immunohistochemical study analyzed and monitored over time, by comparison
between the two groups, 52 parameters for each patient, starting with the usual epidemiological
factors (age, weight, height, body mass index, personal or family medical history, etc.), continuing
with those related to fertility and other clinical issues (chronic pain, metrorrhagia, number of births,
recurrent miscarriage, etc.), up to intraoperative parameters (duration of surgery, blood loss, pelvic
drainage, the need for blood transfusion) and finally, histopathological aspects. We present in this
article some of the results of our study, those related to the quality of the endometrium in the
fibromatous uterus and the influence that uterine fibroid had on the fertility of our patients.
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