THE MULTIDISCIPLINARY APPROACH IN A CASE OF PEDIATRIC EWING’S SARCOMA

Ana-Maria Petrone1,Mădălina Macadon2, Gh. Burnei 1,2,Ș. Gavriliu1,2, Raluca Ghiță1,2
1“Carol Davila” University of Medicine and Pharmacy, Bucharest
2The Emergency Hospital for Children "Maria Sklodowska Curie", Bucharest
Corresponding author: Ana-Maria Petrone
Phone no. 0040724812923
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Ewing's Sarcoma is a rare, malignant osseous tumor arising from undifferentiated cells originating from the neural crest; however it may also develop in the soft tissue. The initial evaluation of a patient who is suspected to be suffering from Ewing's Sarcoma entails taking a thorough medical history along with performing a detailed physical examination. Our patient was diagnosed with Ewing's Sarcoma upon seeking medical attention due to the sudden appearance of pain in his left hip. The medical staff conducted a series of investigations including X-rays, MRI, CT and 3D-CT scans of the inferior limb and pelvis in order to yield the diagnosis of Ewing's Sarcoma; however, the definitive diagnosis was confirmed only by the biopsy performed before the surgery for modular endoprotesation. The patient received preoperative chemotherapy (in order to reduce the tumor dimension) according to the EuroEwing 2008 Protocol. After the seventh course of chemotherapy, surgery was performed, consisting of in-block resection of the proximal left femur and hip joint, followed by the insertion of a modular femoral endoprosthesis. Postoperative follow-up, however necessitated another six courses of chemotherapy.

Keywords: Ewing's sarcoma, chemotherapy, EuroEwing 2008, block resection, modular endoprosthesis

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