SECONDARY HYPERPARATHYROIDISM ASSOCIATED WITH CHRONIC KIDNEY DISEASE. UPDATED REVIEW ON THERAPEUTICAL MANAGEMENT

Maria-Sabina Safta1, M.V. Ghemigian1,2
1The University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania, Romania
2The National Institute of Endocrinology “C.I. Parhon”, Bucharest, Romania, Romania
Corresponding author: Safta Maria-Sabina
Phone no. 0040727500030
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

While a full and complete understanding of the pathogeny of secondary hyperparathyroidism in chronic kidney disease is not acknowledged yet, it is important that this condition has a high impact on the mortality and morbidity of dialysis patients. The intention of this review is to take us on a short journey to understand a bit more about this associated conditions and to explore how a treatment may be assembled to the best possibility at this point in time. From the basis of physiopathology we can state that in chronic kidney disease the hyperparathyroidism appears as a result of low renal function and its alteration of phosphor-calcemic homeostasis. The discussion between the borderline of medical therapy and a surgical approach is crucial. The correct administration of treatment following strictly the therapeutical scheme is absolutely mandatory. Furthermore, in the advanced cases the experience of the surgeon may be a barrier between the life and death of the patient.

Keywords: secondary hyperparathyroidism, chronic renal disease, therapy

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